Markets and institutions, increasingly interconnected, are being challenged by the dizzying pace of change in the financial system, accelerating the buildup of risk and threats to solvency. Regulatory adaptations add another layer of complexity to the issue. Increasingly sophisticated algorithms and the rise of generative artificial intelligence may create new vulnerabilities across the system as banks, nonbank financial institutions, and financial markets exploit nascent opportunities. The conference will explore how firms and markets can become resilient or even antifragile and how regulators can encourage and shepherd, or at least not derail, needed changes.